Ciprofloxacin
Category: Antiinfective It is and isotonic ,sterile aqueous solution of ciprofloxacin lactate, a potent fluoroquinolone derivative with bactericidal activity against a wide rang of gram-positive & gram- negative pathogenic bacteria. It inhibitis bacterial DNA gyrase (Topoisomerase 11) , the enzyme responsible for introducing negative supercoils into the bacterial DNA. This leads to disruption of DNA structure and the death of bacteria.
Indications: EYE :Acute & subacute conjunctivitis, mucopurulent conjunctivitis, blepharoconjunctivitis, blepharitis, bacterial corneal ulcer with or with out hypoopyon, bacteraial keratitis and kerato conjunctivitis chronic dacryocystitis , meibomanitis, preoperative prophylaxis in ocular surgery, treatment of post operative infections.
Ear: Otitis externa, acute otitis media, chronic suppurative otitis media & prophylaxis during oticsurgeries such as mastoid surgery.
Dosage: Ocular infections : 1-2 drops into the affected eye(s) every 4 hrs.Ear: 2-3 drops every 2-3 hrs.
Contra Indications: Hypersensitivity.
Special Precautions: Not for injection. If irritation persists or increases, discontinue. Donot touch the dropper ,since this may contaminate soln.
Side Effects: Mild transient smarting sensation & conjunctival congestion.
 
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