Amrinone Injection
It is a phosphodiesterase enzyme inhibitor which increases force of contraction of heart.
Composition : 100mg/20ml
Indications : CHF
Contraindications : Hypersensitivity
Safety Profile : Fluid and electrolyte imbalance, cardiomyopathy, aortic diseases, aortic diseases, pregnancy and lactation.
Adverse Effects : Cardiac arrhythmias, nausea, hepatotoxicity, hypotension, G.I.Disturbances.
Drug Interactions: Enhanced hypotensive response when used with disopyramide.
Dosage: Loading dose 0.75 mg/kg/i.v.
Milrinone : I. V. administration.
Indications : Short term management of CCF in patient unresponsive to digitalis diuretics or vasodilators
Contraindications : Hypersensitivity
Adverse Effects : Ventricular arrhythmias, hypokalemia, tremors.
Dosage : Initially start with 0.5 mg/kg. Followed by intravenous infusion at a rate of 375-750 nanograms/kg/min.
Purity : Not less than 99%.
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