Gentamicin Injection

Category: Antibiotics and Anti Inefectives
Each vial contains:
Antibiotics and Anti Inefectives
Quality Specification:
Chromatographic Purity - NLT 99.5%
Pack Size: 2ml,30 ml vial

 

Composition : 20mg/2ml, 40mg/1ml, 80mg/2ml, 400mg/10ml,1200mg/30ml
Gentamicin: Potent antibiotic having a broader spectrum of action against a wide variety of bacterial infections.
Indications : Valuable in critically ill patients, with impaired host defence, burns, urinary tract infections, lung abscesses, osteomyelitis, middle ear infection, septicaemia, meningitis caused by gram negative bacilli.
Dosage : 3-5 mg/kg body wt IM or IV daily in 3 divided doses for 7 to 10 days, 25-50 mg/kg/day
Contra-Indications: 25-50 mg/kg/day.
Contra-indications :- Uraemia, severe renal function impairment; pregnancy, neonatals (except in life threatening situations)
Special Precautions: Dose of gentamicin must be precisely calculated according to body wt and level of renal function.
Paediatrics : Reduced dose necessary.
Elderty: Reduced dose may be necessary due to adverse effects.
Side Effects: Irreversible ototoxicity, nephrotoxicity headache, rashes, thrombocytopenia and joint pain.
Drug Interactions : Increased incidence of toxicity when combined with ethacrynic acid, risk of loss of hearing/kidney failure. Cephalosporins, hydrocortisone & indomethacin potentiate nephrotoxicity, neuro-muscular blocking agents.
Purity : Not less than 99%.
 
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